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KMID : 0978920080090020233
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Korean Journal of Clinical Geriatrics
2008 Volume.9 No. 2 p.233 ~ p.239
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Difference of Body Weight Changes between Only Nicotine Replacement Group and Bupropion Combination Group after 6 Weeks of Smoking Cessation
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Lee Sang-Yeoup
Kim Yun-Jin
Lee Jeong-Gyu
Kim Young-Joo
Jung Dong-Wook
Kim Min-Seok
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Abstract
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Background: The suppressive effect of bupropion for weight gain after smoking cessation was already known, but studies about whether the combination therapy of nicotine replacement therapy and bupropion has better suppressive effect for weight gain after smoking cessation than nicotine replacement therapy alone have been rare. The purpose of this study was to evaluate this subject along with a domestic project for smoking cessation in Republic of Korea.
Methods: 70 males had started smoking cessation from January in 2007, and succeeded in ceasing smoking for 5 months by visiting a smoking clinic of a health center in Pusan. The patients were divided into two groups which are the group of nicotine replacement therapy alone and nicotine replacement therapy with bupropion therapy. Weight, body mass index, expiratory carbon monoxide amount and blood pressure of two groups were compared and analyzed.
Results: The rates of increment of weight of two groups had no significant differences. Negative correlation was represented between the average of weight at the 6th week and the averages of age and duration of smoking. Positive correlation was represented between the average of number of cigarettes and baseline weight.
Conclusion: Nicotine replacement therapy alone and nicotine replacement therapy with bupropion therapy have the similar rate of increment of weight after 6 weeks of smoking cessation.
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KEYWORD
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Smoking cessation, Weight loss, Nicotine replacement therapy, Bupropion
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